2021
Publications
New Kendomycin Derivative Isolated from Streptomyces sp. Cl 58-27
New Scabimycins A-C Isolated from Streptomyces acidiscabies (Lu19992)
Bonsecamin: A New Cyclic Pentapeptide Discovered through Heterologous Expression of a Cryptic Gene Cluster
Cyclofaulknamycin with the Rare Amino Acid D-capreomycidine Isolated from a Well-Characterized Streptomyces albus Strain
Superior production of heavy pamamycin derivatives using a bkdR deletion mutant of Streptomyces albus J1074/R2
Microparticles enhance the formation of seven major classes of natural products in native and metabolically engineered actinobacteria through accelerated morphological development
Multiple copies of the oxytetracycline gene cluster in selected Streptomyces rimosus strains can provide significantly increased titers
A Promiscuous Halogenase for the Derivatization of Flavonoids
Composition of nutrient media and temperature of cultivation imposes effect on the content of secondary metabolites of Nocardiopsis sp. isolated from a Siberian Cave
Discovery and Heterologous Production of New Cyclic Depsibosamycins
Engineering the precursor pool to modulate the production of pamamycins in the heterologous host S. albus J1074
Genetically engineered rpsL merodiploidy impacts secondary metabolism and antibiotic resistance in Streptomyces
Towards the sustainable discovery and development of new antibiotics
Marcus Miethke, Marco Pieroni, Tilmann Weber, Mark Brönstrup, Peter Hammann, Ludovic Halby, Paola B Arimondo, Philippe Glaser, Bertrand Aigle, Helge B Bode, Rui Moreira, Yanyan Li, Andriy Luzhetskyy, Marnix H Medema, Jean-Luc Pernodet, Marc Stadler, José Rubén Tormo, Olga Genilloud, Andrew W Truman, Kira J Weissman, Eriko Takano, Stefano Sabatini, Evi Stegmann, Heike Brötz-Oesterhelt, Wolfgang Wohlleben, Myriam Seemann, Martin Empting, Anna K H Hirsch, Brigitta Loretz, Claus-Michael Lehr, Alexander Titz, Jennifer Herrmann, Timo Jaeger, Silke Alt, Thomas Hesterkamp, Mathias Winterhalter, Andrea Schiefer, Kenneth Pfarr, Achim Hoerauf, Heather Graz, Michael Graz, Mika Lindvall, Savithri Ramurthy, Anders Karlén, Maarten van Dongen, Hrvoje Petkovic, Andreas Keller, Frédéric Peyrane, Stefano Donadio, Laurent Fraisse, Laura J V Piddock, Ian H Gilbert, Heinz E Moser, Rolf Müller
Saarland University
Pharmaceutical Biotechnology
Building C2 3
Room 1.27
66123 Saarbrücken
Germany